| Characteristic | Details |
|---|---|
| Generic Name | Dapoxetine |
| Common Dosage | 30 mg, 60 mg |
| Form | Tablet |
| Primary Use | Premature Ejaculation |
| Time to Peak Concentration | 1-2 Hours |
| Half-Life | 1.5 Hours |
| Link | Learn More |
Pharmacokinetics
Dapoxetine 60 mg is a short-acting selective serotonin reuptake inhibitor. This characteristic enhances its role in treating premature ejaculation. Absorption is swift with oral administration. The compound reaches peak plasma concentrations within one to two hours. Its rapid onset of action aligns with its brief half-life of approximately 1.5 hours. Metabolism occurs primarily in the liver via cytochrome P450 enzymes, particularly CYP2D6 and CYP3A4. Excretion is mainly renal. Understanding these pharmacokinetic properties is vital for optimal dosing.
The pharmacokinetic profile ensures a prompt effect. Its short half-life reduces the risk of accumulation in the system. This makes dapoxetine 60 mg suitable for on-demand use. The medication offers a balance between efficacy and safety. Adjustments in dosage are usually unnecessary in mild to moderate renal impairment.
Dapoxetine Use
Dapoxetine 30 mg is prescribed primarily for men diagnosed with premature ejaculation. The typical use involves taking the medication one to three hours before anticipated sexual activity. Clinical trials highlight its efficacy in prolonging ejaculation time. This offers men enhanced control over their sexual activity.
Instructions advise against daily use. Instead, it’s an as-needed medication. Its effectiveness and safety profile are supported by numerous studies. Improvements in intravaginal ejaculation latency time have been documented, enhancing sexual satisfaction.
Who Can and Cannot Take Dapoxetine
Not all patients are ideal candidates for dapoxetine. Suitable individuals include men aged 18 to 64 with a confirmed diagnosis of premature ejaculation. It’s contraindicated in those with heart failure, significant cardiac conditions, or psychiatric disorders like depression.
Older adults over 65 should avoid dapoxetine due to a lack of sufficient safety data. Patients with severe hepatic impairment should not use it either. A full medical evaluation is crucial before initiation.
Cautions with Other Medicines
Potential interactions exist between dapoxetine 30 mg and certain medications. Combining with monoamine oxidase inhibitors is contraindicated. Caution is required when co-administered with potent CYP3A4 inhibitors.
Use alongside other serotonergic drugs can lead to serotonin syndrome. Careful consideration is essential when combined with thioridazine, lithium, and tryptophan. Alcohol use should be minimized due to potential additive effects on cognitive impairment.
Dapoxetine Signs and Symptoms of Overdose
An overdose of dapoxetine 60 mg can manifest through various symptoms. Common signs include dizziness, nausea, and vomiting. Patients may experience increased heart rate and agitation.
Severe overdose cases could result in seizures. Immediate medical attention is required. Supportive care and symptomatic treatment remain the primary interventions.
Purchase Dapoxetine No Prescription
Acquiring dapoxetine without a prescription is not advised. A healthcare provider’s assessment is necessary to ensure safe and effective use. The medication’s profile requires professional oversight.
Pharmacies should only dispense it with a valid prescription. This guarantees appropriate dosing and management of potential side effects. Engaging in unsupervised acquisition can pose serious health risks.
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